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| Lexington Medical Center Located in West Columbia and part of the Lexington County Health Services District. | |
| Piedmont Healthcare System Headquartered in Rock Hill, South Carolina, serves York, Chester and Lancaster county areas. Part of Tenet Healthcare. | ||
| Carolinas HealthCare System Network of nonprofit facilities whose services include behavioral health, emergency care, brain and spine treatment, cancer treatment and senior care. | ||
| Palmetto Richland Memorial Hospital Teaching hospital associated with The University of South Carolina. Located in Columbia. Member of Palmetto Health Alliance. | ||
| Spartanburg Regional Hospital System Headquartered in Spartanburg, South Carolina. | ||
| Carolinas Hospital System - Kingstree 76-bed community hospital. Formerly Williamsburg County Memorial. | ||
| Bon Secours Health System, Inc. Includes St. Francis Hospital, Charleston; Roper Hospital, Charleston; Roper Hospital North, North Charleston. | ||
| Saint Eugene Medical Center Located in Dillon. Part of McLeod Health system. | ||
| McLeod Regional Medical Center Located in Florence, South Carolina. | ||
| Carolinas Hospital System Hospital system in the Pee Dee Region of South Carolina, | ||
| Carolinas Hospital System - Lake City 48-bed hospital serving Lake City and neighboring towns. | ||
| Palmetto Health Alliance Integrated system includes Palmetto Richland Memorial Hospital and Palmetto Baptist Medical Center -- Columbia and Easley. | ||
| East Cooper Regional Medical Center Part of Tenet HealthSystem. Located in Mt. Pleasant. | ||
| McLeod Health System Locally owned, nonprofit health system that serves northeastern South Carolina. | ||
| Wilson Medical Center 50 bed facility located in Darlington. Part of McLeod Health system. | ||
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